Use for migraine, cost, how it works, and more

Qulipta can cause mild or serious side effects. The following lists contain some of the key side effects that may occur while taking Qulipta. These lists do not include all possible side effects.

For more information about the possible side effects of Qulipta, talk with your doctor or pharmacist. They can give you tips on how to manage any side effects that may be concerning or bothersome.

Note: The Food and Drug Administration (FDA) tracks side effects of drugs it has approved. If you would like to notify the FDA about a side effect you’ve had with Qulipta, you can do so through MedWatch.

Mild side effects

Mild side effects* of Qulipta can include:

Most of these side effects may go away within a few days or a couple of weeks. However, if they become more severe or don’t go away, talk with your doctor or pharmacist.

* This is a partial list of mild side effects from Qulipta. To learn about other mild side effects, talk with your doctor or pharmacist, or view Qulipta’s prescribing information.
† For more information about this side effect, see “Side effect details” below.

Serious side effects

Serious side effects from Qulipta weren’t reported in clinical trials of the drug, but it’s possible they may still occur. Call your doctor right away if you have serious side effects. Call 911 or your local emergency number if your symptoms feel life threatening or if you think you’re having a medical emergency.

Allergic reaction is a possible serious side effect of Qulipta. For more information about this side effect, see “Side effect details” below.

Side effect details

Here’s some detail on certain side effects this drug may cause.

Nausea

In clinical trials, nausea was the most commonly reported side effect in people who took the drug. It was slightly more common in people who took higher doses of the medication.

It’s important to note that nausea is also a common symptom of migraine episodes, which Qulipta is used to help prevent. It’s still possible to have migraine episodes while taking Qulipta. (To learn more about other drugs that may be used with Qulipta, see the “Qulipta use with other drugs” section above.)

What you can do

Nausea from Qulipta may ease as your body gets used to the medication. Taking your daily dose with food may also help.

If you have nausea that’s bothersome or severe while taking Qulipta, talk with your doctor about ways to manage this side effect. They may recommend taking a lower dose of Qulipta. Or they may suggest taking antinausea medication, such as ondansetron (Zofran) or promethazine (Phenergan).

Constipation

Constipation may occur while taking Qulipta. In clinical trials, constipation was among the more common side effects reported with the drug. It was slightly more common in people who took higher doses of the medication.

What you can do

You may be able to ease constipation due to Qulipta with simple lifestyle changes. These include getting enough gentle exercise, drinking plenty of fluids, and increasing the amount of fiber in your diet.

If you have constipation that’s severe or doesn’t go away, talk with your doctor or pharmacist. They may recommend taking a laxative medication. They may also recommend taking a lower dose of Qulipta.

Fatigue and tiredness

Fatigue, tiredness, or sleepiness may occur while taking Qulipta. These side effects were among the more common side effects reported with Qulipta in clinical trials. They were slightly more common in people who took higher doses of the medication.

Keep in mind that you may also have fatigue and tiredness before, during, and after a migraine episode. It’s still possible to have migraine episodes while taking Qulipta. (To learn more about other drugs that may be used with Qulipta, see the “Qulipta use with other drugs” section above.)

What you can do

If you have fatigue, tiredness, or sleepiness while taking Qulipta, you should not drive or do other potentially dangerous activities, such as using machinery.

These side effects may ease as your body gets used to the medication. However, if you have fatigue or tiredness that’s severe or bothering you, talk with your doctor or pharmacist. They may recommend a lower dose of Qulipta. Or they may recommend switching to a different medication to help prevent migraine.

Allergic reaction

Allergic reaction wasn’t reported in clinical trials of Qulipta. However, as with most drugs, some people can have an allergic reaction after taking Qulipta.

Symptoms of a mild allergic reaction can include:

A more severe allergic reaction is rare but possible. Symptoms of a severe allergic reaction can include:

  • swelling under your skin, typically in your eyelids, lips, hands, or feet
  • swelling of your tongue, mouth, or throat
  • trouble breathing

Call your doctor right away if you have an allergic reaction to Qulipta, as the reaction could become severe. Call 911 or your local emergency number if your symptoms feel life threatening or if you think you’re having a medical emergency.

https://www.medicalnewstoday.com/articles/drugs-qulipta